| 1. | It is caused by a deficiency of the enzyme xanthine oxidase.
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| 2. | This pathway also is independent of the enzyme activity of xanthine oxidase.
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| 3. | By inhibiting xanthine oxidase, it reduces uric acid production.
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| 4. | Inhibition of xanthine oxidase has been proposed as a mechanism for improving cardiovascular health.
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| 5. | *Alloxanthine is an inhibitor of xanthine oxidase.
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| 6. | AO is very similar in amino acid sequence to xanthine oxidase ( XO ).
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| 7. | Xanthine oxidase inhibitors block uric acid production.
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| 8. | Other enzymes capable of producing superoxide are xanthine oxidase, NADPH oxidases and cytochromes P450.
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| 9. | The active metabolite of allopurinol is oxypurinol, which is also an inhibitor of xanthine oxidase.
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| 10. | This activity is often found in a bifunctional enzyme with xanthine oxidase ( ) activity too.
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